Som-Neo (zopiclon) 7.5mg #40 tab
Sleeping
Sleeping
International nonproprietary name: Zopiclone.
Dosage form: white, cylindrical, 7 mm in diameter with a bitter taste of the tablets.
Ingredients: Zopiclone - 7.5 mg;
Other ingredients: lactose, polyvinylpyrrolidone, starch, magnesium or calcium stearate, talc.
Pharmacological action: sleeping;
Pharmacological properties:
Zopiclone is a new group of psychotropic drugs - tsiklopirolonebis first representative. It has a hypnotic, sedative, trankvilizatsiuri, anticonvulsant and muscle relaxant action. Zopiclone enhance the deterrent effect of gamma-aminoerbomzhavas CNS receptors, thus inhibits neural transmissions in different districts of the central nervous system.
,, Ar-me-Neo '' sleepiness causes a rapid (30 minutes) and reduces the number of nocturnal awakenings, increases sleep duration, improves its quality without changing the structure.
Drug addictions, does not develop its long-term (17 weeks), even.
Pharmacokinetics:
Zopiclone is rapidly absorbed from the gastrointestinal tract after oral administration of. Maximum plasma concentration is reached after 1.5-2 hours. Zopiklonis linked to plasma proteins is approximately 45%; After repeated administration and its metabolites are not zopiklonis accumulation. The main metabolites N- oxide products (pharmacologically active) and N- dimetiluri metabolite (pharmacologically inactive). Their half-lives of 4.5 and 7.4 hours, respectively.
Show: transient, situational and treatment of chronic insomnia (sleep initiative whistling, awakening at night and early morning awakening).
Dosage:
Drug should be as far as possible in a short period of time, no more than 4 weeks. Treatment may be repeated only after assessing the condition of the patient.
Using the drug becomes orally at bedtime.
Transient insomnia treatment duration is 2 to 5 weeks. Situational insomnia - 2 to 3 weeks. Chronic insomnia length of treatment is determined by your doctor.
The recommended dose for adults is 7.5 mg compiles.
Elderly patients, patients with impaired liver function or chronic respiratory insufficiency drug prescribed dose of 3.75 mg and, if necessary, increase the dose from 7.5 mg.
Renal failure patients should start treatment with 3.75 mg is recommended, however, and its metabolites accumulation zopiklonisa this category of patients is observed.
Neo Ar-me-up for patients under 18 years is not recommended.
Side effects:
• Often: bitter or metallic taste in the mouth; Possible - dyspepsia, nausea, dry mouth.
• headache, dizziness, drowsiness.
• anterograde amnesia; Rarely - mental and paradoxical reactions (nightmares, irritability, hallucinations, aggressiveness, thinking disturbances, lethargy, movement coordination disorders, depression).
• Allergic reactions: skin rash, itching; In exceptional cases - angioedema, anaphylactic reactions.
Contraindications:
Hypersensitivity to the drug and other components including zopiklonisa; Myasthenia gravis; Respiratory failure; Severe liver failure; During sleep apnea syndrome; Breast-feeding; Pregnancy; 18 years of age;
Use in pregnancy and lactation:
The drug should not be used during pregnancy and lactation.
Special instructions:
,, Ar-me-Neo '' - the use of the drug dependence risk is minimal, however, can not be absolutely ruled out drug addiction and abuse of this fact.
Drug dosage and duration of treatment increases the risk of addiction to the violation, or other psychotropic drugs, with alcohol intake.
After a long course of therapy is recommended to reduce the dose gradually to avoid rebound insomnia and withdrawal syndrome risk.
If you have a place to sleep after taking the drug or drug administration before going to the termination of a significant period of time has passed, it is possible to develop anterograde amnesia. To avoid the tablet should be taken at bedtime, sleep duration must be at least 6 hours.
Ar-me-Neo Caution must be exercised in patients with depression, because it does not cure depression and may only mask the symptoms.
Can not drink alcoholic beverages during treatment.
Influence of vehicle and mechanisms management:
,, Ar-me-Neo "is not allowed to drive or to operate machinery after taking that demand attention and psychomotor speed of reaction.
Overdose:
Symptoms: CNS depression, which is observed in the complex of symptoms of drowsiness to coma and depending on the dose. It is possible to develop amnesia, blurred vision, instability, apathy, ataxia, incoordination.
Treatment: First aid - gastric lavage. If necessary - symptomatic therapy is recommended for stationary conditions. Special attention should be paid to respiratory and cardiac normalization. Benzodiazepine receptor antagonist may be in the form of an antidote - flumazenil use.
Interaction with other drugs:
,, Ar-me-Neo '' - by neuroleptics, sleeping drugs, tranquilizers and sedative drugs, anesthetics, sedative action of antihistamine drugs, as well as the simultaneous application of erythromycin observed in the central nervous system depressant action.
,, Ar-me-Neo '' reduces the plasma concentration trimipraminis.
Simultaneous use of ethanol is not recommended, as it may increase the sedative effect zopiklonis.
Caffeine reduces,, Ar-me-Neo '' - s effectiveness.
Pharmacy Issue:
Pharmaceutical product group II - issued a doctor's prescription.
Storage:
Store in a dry, protected from light and the reach of children, no more than 25 º C temperature.
Visual defects of the preparation can not be!
Packing:
Primary Packaging: 20 tablets in PVC / Alu-contour cellular packaging.
Used packaging into cardboard box with 2 blisters.
Shelf life: 2 years.
