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Vitamini C 1000mg #10 tab (effervescence)
Vitamin mean



Pharmacological group: Vitamin mean.
 
Composition: Ascorbic acid –  1000 mg;
 
Aiding substances: Orange aromatizer; waterless citric acid; sodium bicarbonate, sodium carbonate; lactose anhydrite; saccharin; polyvinylpyrrolidone and polyethylene glycol;
 
Description: White or beige color pills with slightly hairy surface, yellow color inserts is permissible.
Pharmacological operation:  Vitamin C is characterized with multilateral actions:
 
It is one of the strong antioxidant. It immobilizes free radicals, formed in the process of muscles intensive work  and prevents its harmful influence on the organism’s tissues;
At time of collagen synthesis, protein performs the principal role, which presents principal determinative factor of growth and connecting tissues, teeth and bone restoration; hastens healing of wounds and scorches.
Regulates formation of steroid hormone;
Stimulates generation of interferon, which prevents reproduction of viruses;
Strengthens immune system;
Provides generation of energy on the cell level, participates in ATP synthesis;
Usage of C vitamin is especially recommended for smokers;
Reduces level of cholesterol in blood and conduces normalization of arterial pressure;
At time of stress, megadose of vitamins’ protects cells from disorganization; it restores organism’s power and immunity.
 
 
Indication: Take of vitamin C is recommended:
 
At time of cold; acute respiratory- grippal infections; weakened immunity; increased physical and mental activity; tiredness; asthenic condition; eczema; asthma; atherosclerosis; fungus diseases; eye’s diseases; gums’ inflammation; skin diseases; wounds and recovery after diseases;
Contra-indication: Additional sensitivity; hypercoagulation – in case of taking great dose; tendency toward thrombosis; kidney- pebbles disease; 
It should be used carefully at time of hyperoxaluria, kidneys’ insufficiency, hemochromatosis, thalassemia, polycythemia, leukemia, sideroblastic anemia, gluco -6-phosphatedehydrogenesis deficit,  progressed malignant diseases, pregnancy;
Side effects: Vitamin C is easily transferred at time of taking it with great dose, because the organism has ability to excrete unassimilated part of the vitamin.   Taking C vitamin with great dose causes one of he constant fixed symptom of diarrhea; but the dosage, number of taking which causes diarrhea is individual. In case of one and the same person, attitude toward the quantity of the vitamin changes according to the circumstances; it has great resistance toward the stress condition or illness, intestine tract and great amount of ascorbic acid, because demand of the organism toward the vitamin increases.
 
There rarely may be revealed the following side effects:
 
From side of central nervous system: headache, feeling of tiredness, excitability of CNS – in case of taking it with great amount, sleep disorder. 
From side of food digest system: irritation of intestine tract mucous tunic, nausea, vomiting, diarrhea, stomach spasm; 
From side of endocrine system: suppress of insular unit function of the pancreas gland;
From side of urine excrete: in case of great dose usage – hyperoxaluria and formation of boulders from calcium oxalate, which damages glomerulous apparatus of the kidney;
From side of heart blood-vessels: decrease of capillary pass and worsening of tissue feed, thrombosis; 
In great dose: increase of arterial pressure, development of microangiopathy microcardiodystrophy;
 
Allergic reactions:  rash on the skin, hyperemia, rarely - anaphylactic shock;
 
Safety of usage:  Several years ago there was the idea, that taking C vitamin with great dose could have caused formation of stones in the kidneys, because ascorbic acid dissolves with generation of sorrel’s acid; it is one of the principal components which forms boulders in the kidney (sorrel’s acid calcium salt). There wasn’t revealed significant intensification of the boulders’ generation in those patients who take C vitamin with great dose from 15 to 30 gram in a day or more for a long time. 
Great doses (above mentioned quantity) may cause hemolysis (dissolutionof blood’s red cells) in those people who can’t generate specific enzyme - gluco -6-phosphatedehydrogenesis. So, people who have such successive disorder have to take C vitamin with great dose under the doctor’s supervision.  
If you take ascorbic acid 1 gram or more 3 times in a day, you should control vitamin B12 compound in blood in every 6 months. 
Using rule and dosage: The preparation is taken perorally after eating. 1 pill is soluted in 1 glass of water (200 milliliter).  Swallow, chew and sniveler is forbidden;
In adults: 500 milligram  1 or 2 times in a day after eating (or according to the doctor’s recommendation);
For prophylactic – 250 milligram 1-2 times in a day;
Duration of treatment course: 3-4 weeks.  
Package: 10 sparkling pills in polymer material produced tube with tight lid. Etiquette is stack on the tube and put in carton box.
Storage conditions: Is kept in a dry, cool and dark place. After the expire or defect as a result of visual check usage of preparation is forbidden.



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