Dosage form: Gel.

Pharmacological group: non-steroidal anti-inflammatory drugs.

International arapatenturi Name: Diclofenac 25 g

 

Ingredients:

 

Active substance: diclofenac sodium - 0.25 g;

 

Other ingredients: dietilaminis hydrochloride, dimethylsulfoxide, alcohol 95%, methylparaben, carbomer, water, sodium hydroxide, peppermint oil.

Mode of action:

Pharmacokinetics: Diclofenac is a nonsteroidal anti-inflammatory analgesic and antipyretic effect.

The mechanism of action of the drug plays a role in the inhibition of prostaglandin biosynthesis by diclofenac, which is related to the enzyme cyclooxygenase-1 and cyclooxygenase-2's suppression of the activity.

The drug reduces inflammation and pain, swelling and improve circulation.

Pharmacokinetics is partially absorbed by the skin when applied topically. Diclofenac points proportional to the contact time and the markings on the skin area. Bioavailability is - 6%, plasma protein binding of 99.7% is excreted by the kidneys.

Indications:

 

Inflammatory and degenerative diseases of the musculoskeletal system:

Rheumatoid arthritis, psoriatic, chronic arthritis, ankylosing spondylitis, gout and other metabolic arthritis, osteoarthritis of the spine and joints;

Rheumatic soft tissue injuries: joints, muscles, tendons, ligaments traumatic injuries.

And post-traumatic inflammation of soft tissues and joints: stretching, and damage as a result of the load.

Side effects: allergic reactions, drug hypersensitivity case.

Local reactions: eczema, photosensitivity, contact dermatitis (redness, peeling, itching).

Long-term use or large area of ​​the body may occur as a result of the action of the resorptive be provided diclofenac systemic side effects: dizziness, headache, epigastric pain.

Side effects of the drug use and consult a doctor if the patient has to stop.

Dosage and administration:

Adults and children older than 12 years of gel applied in a thin layer and gently rubbed into the damaged place 3-4 times a day.

Given that only 6% of the external application of diclofenac absorbed, children 6 to 12 years of gel applied to no more than 2 times a day with a doctor's recommendation.

The duration of treatment depends on the indication and the effectiveness of the treatment (in order to strengthen the effect of diclofenac gel used with other forms). Its use without consulting a doctor should not exceed 2 weeks.

Missed dose: the drug dose is missed, the gel should be affixed on or as soon as possible to the original scheme.

Contraindications:

 

• hypersensitivity to other nonsteroidal anti-inflammatory agents.

• Do not use during pregnancy and lactation.

• 12 years of age without a doctor's recommendation to use the drug in children is not recommended.

• the integrity of the skin.

Overdose:

 

External use of the drug, diclofenac low systemic absorption of the above, it is impossible to overdose.

In case of overdose can be locally Allergic reactions, burning, itching.

Treatment is symptomatic.

Pregnancy and breast-feeding: Pregnancy and breast-feeding is not recommended.

Influence of vehicle and mechanisms management: the use of the drug does not affect the vehicle and mechanisms management.

Interaction with other drugs: The drug increases the photosensitivity causing means.

Clinically significant interactions with other drugs have not been described.

  

Caution: The following markings on the drug, itching and burning sensation of the skin, rinse with warm water.

Form:

Primary packaging: 25 g Gel aluminum tube.

 

Secondary packing: tube in a cardboard box with instruction.

Shelf life: 2 years.

After the expiry of the drug can not be used or visual defects.

 

Storage conditions: Store no more than 15-25 ° of temperature conditions, dry and dark place.

Pharmacy Issue: pharmaceutical product group - III (obtained without a prescription).

Manufacturer: Ltd ,, Neopharmi ".

Georgia. Tbilisi. David's 12 km.

Tel / fax: + 995 (32) 259-64-46; 259-57-90.