Physio 0,65% (Sodium chloride) - 10ml nasal drops
mean for nasal cavity diseases.
International name: Sodium chloride
Pharmacological group: Medical mean for nasal cavity diseases.
ATC code: R01AX10.
0,9% solution – nasal spray.
Description: A colorless, transparent solution, weak
Composition: “Physio” nasal drops and spray contains:
Sodium chloride – 6,5mg/1 ml (0,65% solution) or 9 mg/1 ml (0,9%
edetat, sodium dihydrophosphate dihydrate, sodium hydrophosphate dihydrate, distilled water.
"Physio" 0,65% and 0,9% represents sodium
chloride solution (respectively – hypotonic and isotonic), which moistens a
mucous membrane of nasal cavity, dilutes the condensed mucous elution,
facilitates its removal from the nasal cavity, improves nasal breath. Softens
the scab formed on the mucous membrane of nasal cavity and promotes its
removal. The preparation removes puffiness of a mucous membrane of nose and
prevents development of otitis. Also, it should be noted, that when using
during the period of nose post operation, the preparation promotes removal of
dead tissues of skin and scales that reduces bleeding.
Pharmacokinetics: At local use low
• It is used for hygienic processing of mucous
membrane of the nasal cavity for adults and children (0,65% solution – for
babies), for fast and easy clarification of nasal cavity from viscous mucus and
• Inflammatory diseases of various etiology of nasal
cavity mucous membranes, rhinopharynx (infectious, allergic rhinitis, chronic atrophic
rhinitis; rhinosinusitis; rhinopharyngitis), followed by dryness of nose mucous
membrane or flow of slime;
• Prevention of inflammatory processes of nasal
cavity, rhinopharynx, additional nasal sinus (sinusitis, frontitis, sinusitis), prevention of otitis in the period
of epidemic aggravation;
• Cleaning of nasal mucous membranes and moisture in
polluted environment with harmful substances (paints, dust, flour) or in case
of long stay in air-cooling building.
• Post operational period of nose, for removal of dead
tissues of skin and scales.
• During the period of complex treatment, promotes
abortion of other therapeutic agents from nasal cavity.
· Hypersensitivity toward the
components including in the
· 0,9% for nasal spray – children’s age till 1
Side effects: In some cases there may
reveal allergic reactions, which are expressed by irritation of nasal mucous
Order of administration and
agent is used intranasal.
0,65% nasal drops:
for children up to 1 year: 1 drop in each nostril; children more than one year:
1-2 drop in each nostrils 3-4 times in a day. For adults: 2 drops in each
nostril 3-4 times in a day.
0,9% nasal spray:
hold the bottle in vertical position and spray the solution in each nostril.
After 2-3 minutes from spray, nasal cavity should be cleaned. In adults and
children more than 3 years - 2 sprays of 0,9% spray 3-4 times in a day (more is
possible in case of need).
For children from 1 to 3 years:
1 spray of 0,9% spray 3-4 times in a day.
For preventive treatment the
preparation may be administered 1-4 times in a day.
Duration of treatment course is
three weeks; the second course of treatment may be carried out after 30 days
rest. At time of preventive treatment, it is necessary to clean the nasal
cavity before use of preparation.
Special instructions: In order to avoid spread of
infection, use of one vial isn’t recommended by various people.
After administration clean the
bottom of the vial.
Pregnancy and lactation: Use of “Physio” during
lactation and pregnancy is recommended.
Interaction with other medicines: Because of low absorption ability, interaction
with other preparations isn’t revealed.
Package: 10 ml 0,65% solution in polyethylene vial with
dropper. The vial is placed in carton box with annotation.
30 ml 0,9% solution white
colour high-density polyethylene spray vial with sprayer. The vial is placed in
carton box with annotation.
Storage: Is kept in a dark place, not more than 250C.
After opening, the preparation
is valid till 1 month.
After the expiry date, the preparation should not be used.
Drug release form: Group of pharmaceutical product -
III (without prescription).
Shelf life: 2 years.