Deprenol 40 tablets
Paramedical mean
Pharmacological group: Antidepressant activity phytopreparatio
ATC code: NO6AX25
Tablet content: Each pill contents as active substance extract of hypericum with 0,3mg anthracenes content (recalculated to hypericin).
Pharmacological operation: Main biologically
active substances of hypericum extract compounding in the preparation:
hypericin, pseudohypericin, hyperforin and flavanoids that improve
central and autonomic nervous system functioning.
The preparation makes anxiolytic and antidepressant
action: improves psycho-emotional condition, mood, removes apathy,
depression, regulates sleep, and increases psychical and physical
activity.
Indication:
· Psychovegetative disorders (apathy, mood depression);
· Neurotic reactions;
· Mild and moderate depression accompanied by anxiety (including related to climacteric syndrome).
Side effects:
Allergic reactions: there may develop rash on the skin, itching, eczema;
From the side of CNS: anxiety, headache, feeling too tired;
From the side of gastro-intestinal disorders: nausea, abdominal pain (epigastric area);
From the side of hematopoietic organs: iron deficiency anemia.
Contraindication: Hypersensitivity to any
component, compounding in the preparation; severe depression,
co-administration of MAO-inhibitors-antidepressants, simultaneous
administration of preparations having influence on blood coagulation
(Varfarin, and other indirect anticoagulants), children’s age up to 12
years (due to insufficient data), influence of ultra-violet rays (it is
necessary to avoid straight sun rays during the treatment period).
Order of administration: In adults and children over the 12 years is administered 1 tablet 2-3 times in a day at time of eating.
Duration of treatment is 2-4 weeks (not more than 6
weeks). Optimal effect is reached when preparation is administered
regularly, one and the same time, not less than 4 weeks. In case of
necessity it is possible to repeat the course after 2-3 weeks.
It should be administered with enough amount of water (without chew).
In case of dose omission, the next dosage should be administered according to the primary scheme, do not take double dose.
Pregnancy and lactation: There are not reliable safety clinical data of preparation usage during pregnancy and lactation period.
Interaction with other medicaments and other interaction: Co-administration
reduces effectiveness of indirect anticoagulants (Fenprokumoni,
Varfarin), Midazolam, Digoxin, Amitriptyline, Benzodiazepin,
Nortriptyline, Teophylline, Verapamil.
Co-administration with some antidepressants, such as
Nephazodon, Paroxetin, Sertralin, Triptanam may reinforce their action
and reveal such symptoms as nausea, vomiting, fare, anxiety, confusion.
The preparation strengthens photosensitivity action of
some medicaments, such as Tetracyclines, Sulfanilamide, Thiazide
diuretics, Quinolones, Piroxicam.
Prolongs sleep caused by general anesthetics and narcotic
analgesics, but shortens the sleep caused by barbiturates. Reduces
hypotensive effect of Reseprine, increases theophylline metabolism
speed.
Influence of preparation on the ability of vehicle and mechanisms management: The
patient who intakes this preparation should be carefully during working
with those mechanisms that require attention concentration.
Production form: Primary package: 10 tablets on the pvc/alu blister.
Secondary package: 4 blisters in the carton box with instruction.
Shelf life: 3 years.
In case of visual defects or expiry of validity date the preparation can not be used.
Storage conditions: Store not more than 250C in a dry, protected from light place. Keep away from children.
Order of issue: III group of a pharmaceutical product - issued without prescription.
Manufacturer: “Neopharmi” LTD...
12th km Davit Aghmashenebeli alley, Tbilisi, Georgia.
Tel/fax: 259 64 46; 259 57 90.
