Josterin #20 capsules
ATC Code: A06AX.
Pharmacological group: Laxative agent.
Drug Form: Capsules.
Composition:
Dismembered fruit of Rhamnus cathartica (Fructus Rhamni catharticae) - 0,297 g.
Aiding substance: Calcium stearate..
Powder of Rhamnus cathartica fruit consists of anthraglycosides (4%),
among them frangulicemodin, chrysofanol, (same as glucofrangulin), ramnoxatin
(frangulin) and frangulic-emodin bioside
- Rhamnus. Powder of the fruit also contains tanning matters, carbohydrate,
organic acids, anthocyanins, pitch, flavonoids (quercite, ramnetin, cempferol,
rhamnocitrine).
Pharmacological operation:
Rhamnus capsules Rhamnus capsules have diarrea action that is stipulated
with containment of anthraglycosides. The above mentioned substances irritate
gut interoceptives and strengthens peristaltic, it acts on large intestine and
stipulates its quick dismantle.
The laxative effect after 8-10 hours. Delayed action of the drug mainly
on the large intestine due to the fact that the collapse of anthraglycosides in
the intestine occurs gradually. The active ingredient in a sufficient amount to
advance laxative effect accumulates only the time to reach the colon.
Indication:
It is used at the time of atonic and spastic constipation. Besides
principal action, it reveals anti-inflammatory, spasmolytic, covering and
bactericidal characteristics. It is recommended at the time of colitis,
hemorrhoids, rectum ulser and wounds.
Contra-indication:
- Additional
sensitivity toward the components compounding in the preparation.
- Hemorrhoidal
bleeding.
Using rule and dosage:
1 capsule once in a
day before sleep, every second day, no matter mealtime. Duration and interval of
taking is determined individually.
Children age: Not known.
Side effects: Abdominal pain, spastic nature, flatulence,
nausea, vomiting, discoloration of urine, allergic reaction.
Caution: The product is assigned caution during
pregnancy and lactation, with liver and / or kidney failure in the
postoperative period in the abdominal cavity.
Pregnancy and lactation: Not known.
Influence on ability
of management of vehicles and mechanisms:
Does not operate.
Interaction with other
medical preparations:
Prevents absorption of
tetracycline.
Production form: 10 capsules on a blister of PVC/aluminum. 2
blisters in a box made of cardboard.
Storage conditions: Store on the room temperature, in a dark, dry
place.
Shelf Life: 2 years.
In case of validity term expiration or visual
survey of defects detection – the preparation using is inadmissible.
Order
of issue: Pharmaceutical
product group III - issued without
prescription.
Manufacturer: "Neopharmi" LTD
12th km, David Agmashenebeli alley, Tbilisi, Georgia
Tel/Fax: +995 (32) 259-57-90; 259-64-46.